The American Cancer Society has expanded colorectal cancer screening guidelines to include a new blood test and additional at-home stool options. The aim is greater accessibility, especially for those who might otherwise skip screening. However, the guidelines still identify colonoscopy as the gold standard.
Unlike blood or stool tests, colonoscopy lets physicians examine the entire colon and remove potentially cancerous polyps in one procedure. Blood and stool tests are less effective at detecting precancerous growths and early cancers, so they are primarily recommended for people who decline or cannot complete colonoscopy.
Positive noninvasive results still require a follow-up colonoscopy — ideally within six months — to confirm findings and take preventive action.
For most average-risk adults, MedBen WellLiving recommends colonoscopy every 10 years starting at age 45. Other tests are better than none, but colonoscopy remains the most complete and effective option for detection and prevention.